Publications

  1. Votteler M, Berrio DAC, Pudlas M, Walles H, Stock UA, Schenke-Layland K. Raman spectroscopy for the non-contact and non-destructive monitoring of collagen damage within tissues. J Biophotonics 5(1): 47–56 Jan (2012)
  2. Brockbank KG, Stock UA, Schenke-Layland K. Reply: Long-Term Storage of Human Heart Valves Above the Glass Transition at −80°C. Ann Thorac Surg 93(2): 695 (2012)
  3. Groeber F*, Holeiter M*, Hampel M, Hinderer S, Schenke-Layland K. Skin Tissue Engineering – In vivo and in vitro applications. Clin Plast Surg. 39(1): 33-58 Jan (2012) (Review)
    *Both authors contributed equally to this work. Republished from Adv Drug Deliv Rev. 63(4-5): 352-66.
  4. Brockbank KG, Schenke-Layland K, Greene ED, Chen Z, Fritze O, Schleicher M, Kaulitz R, Riemann I, Fend F, Albes JM, Stock UA, Lisy M. Ice-free cryopreservation of heart valve allografts: better extracellular matrix preservation in vivo and preclinical results. Cell and Tissue Banking DOI: 10.1007/s10561-011-9288-7 (2012)
  5. Fritze O, Romero B, Schleicher M, Jacob MP, Oh DY, Starcher B, Schenke-Layland K, Bujan J, Stock UA. Age-Related Changes in the Elastic Tissue of the Human Aorta. J Vasc Res 49(1): 77–86 (2011)
    Free Article
  6. Pudlas M, Koch S, Bolwien C, Thude S, Jenne N, Hirth T, Walles H, Schenke-Layland K. Raman spectroscopy - A Non-Invasive Analysis Tool For The Discrimination of Human Skin Cells. Tissue Eng Part C Methods 17(10): 1027-1040 September (2011)
  7. Pusch J, Votteler M, Göhler S, Engl J, Hampel M, Walles H, Schenke-Layland K. The physiological performance of a three-dimensional model that mimics the microenvironment of the small intestine. Biomaterials 32(30): 7469-7478 October (2011)
  8. Schenke-Layland K, Nsair A, Van Handel B, Angelis E, Gluck J, Votteler M, Goldhaber JI, Mikkola HK, Kahn M, MacLellan WR. Recapitulation of the embryonic cardiovascular progenitor cell niche. Biomaterials 32(11): 2748-2756 April (2011)
  9. Schenke-Layland K, Nerem RM. In vitro human tissue models — moving towards personalized regenerative medicine. Adv Drug Deliv Rev 63(4-5): 195-196 April (2011) (Commentary)
  10. Pudlas M, Berrio DAC, Votteler M, Koch S, Thude S, Walles H, Schenke-Layland K. Non-contact discrimination of human bone marrow-derived mesenchymal stem cells and fibroblasts using Raman spectroscopy. Medical Laser Application 26(3): 119-125 August (2011)
  11. Brockbank KG, Wright GJ, Yao H, Greene ED, Chen ZZ, Schenke-Layland K. Allogeneic Heart Valve Storage Above the Glass Transition at -80°C. Ann Thorac Surg 91(6): 1829-1835 June (2011)
  12. Schenke-Layland K. From tissue engineering to regenerative medicine — the potential and the pitfalls. Adv Drug Deliv Rev 26(3): 119-125 August (2011) (Preface)
  13. Groeber F*, Holeiter M*, Hampel M, Hinderer S, Schenke-Layland K. Skin Tissue Engineering – In vivo and in vitro applications. Adv Drug Deliv Rev 26(3): 119-125 August (2011) (Review)
    *Both authors contributed equally to this work.
  14. Votteler M, Kluger P, Walles H, Schenke-Layland K. Stem cell microenvironments – Unveiling the secret of how stem cell fate is defined. Macromol Biosci 10(11): 1302–1315 November 10 (2010) (Review)
  15. Evseenko D, Zhu Y, Schenke-Layland K, Kuo J, Latour B, Ge S, Scholes J, Dravid G, MacLellan WR, Crooks GM. Mapping the first stages of mesoderm commitment during differentiation of human embryonic stem cells. P Natl Acad Sci USA 107(31): 13742–13747 August 3 (2010)
    Free PMC Article
  16. Brockbank KG, Heacox AE, Schenke-Layland K. Guidance for Removal of Fetal Bovine Serum from Cryopreserved Heart Valve Processing. Cells Tissues Organs 193(4) March (2011)
    Free Article
  17. Kluger P, Wyrwa R, Weisser J, Maierle J, Votteler M, Rode C, Schnabelrauch M, Walles H, Schenke-Layland K. Electrospun Poly(D/L-lactide-co-L-lactide) Hybrid Matrix – A Novel Scaffold Material for Soft Tissue Engineering. J Mater Sci 21(9): 2665–2671 September (2010)
    Free PMC Article
  18. Lisy M, Pennecke J, Brockbank KGM, Fritze O, Schleicher M, Schenke-Layland K, Kaulitz R, Riemann I, Weber CN, Braun J, Mueller KE, Fend F, Scheunert T, Gruber AD, Albes JM, Huber AJ, Stock UA. The performance of ice-free cryopreserved heart valve allografts in a orthotopic pulmonary sheep model. Biomaterials 31(20): 5306-5311 July (2010)
  19. Li X, Wu K, Edman M, Schenke-Layland K, MacVeigh-Aloni M, Janga S, Schulz B, Hamm-Alvarez S. Increased expression of cathepsins and obesity-induced pro-inflammatory cytokines in lacrimal glands of male NOD mouse. Invest Ophth Vis Sci 51(10): 5019–5029 October (2010)
    Free PMC Article
  20. Schleicher M, Sammler G, Schmauder M, Fritze O, Huber AJ, Schenke-Layland K, Ditze G, Stock UA. Simplified Pulse Reactor for Real-Time Long-Term In Vitro Testing of Biological Heart Valves. Ann Biomed Eng 38(5) May (2010)
  21. Zhou J, Fritze O, Schleicher M, Wendel HP, Schenke-Layland K, Harasztosi C, Hu S, Stock UA. Impact of heart valve decellularization on 3-D ultrastructure, immunogenicity and thrombogenicity. Biomaterials 31(9): 2549-2554 March (2010)
  22. Fritze O, Schleicher M, König K, Schenke-Layland K, Stock U, Harasztosi C. Facilitated non-invasive visualization of collagen and elastin in blood vessels. Tissue Eng Part C Methods 16(4): 705-710 August (2010)
  23. Schenke-Layland K, Xie J, Magnusson M, Angelis E, Li X, Wu K, Reinhardt DP, MacLellan WR, Hamm-Alvarez SF. Lymphocytic infiltration leads to degradation of lacrimal gland extracellular matrix structures in NOD mice resembling Sjögren’s syndrome-like exocrinopathy. Exp Eye Res 90(2): 223-237 February (2010)
    Free PMC Article
  24. Schenke-Layland K, MacLellan WR. Induced Pluripotent Stem Cells. It's Like Deja Vu All Over Again. Circulation 120(15): 1462-1464 (2009)
    Free PMC Article
  25. Schenke-Layland K, Stock UA, Nsair A, Xie J, Angelis E, Fonseca CG, Larbig R, Mahajan A, Shivkumar K, Fishbein MC, MacLellan WR. Cardiomyopathy is associated with structural remodelling of heart valve extracellular matrix. Eur Heart J 30(18): 2254-2265 (2009)
    Free PMC Article
  26. Schenke-Layland K, Rofail F, Heydarkhan S, Gluck JM, Ingle NP, Angelis E, Choi CH, MacLellan WR, Beygui RE, Shemin RJ, Heydarkhan-Hagvall S The use of three-dimensional nanostructures to instruct cells to produce extracellular matrix proteins that can be used for regenerative medicine strategies. Biomaterials 30(27): 4665-4675 (2009)
    Free PMC Article
  27. Nsair A, Schenke-Layland K. Invited Commentary: Differential Expression of Collagen Type V and XI alpha-1 in Human Ascending Thoracic Aortic Aneurysms. Ann Thorac Surg. 88(2): 513-514 (2009)
  28. Schenke-Layland K*, Strem BM*, Jordan MC, DeEmedio MT, Hedrick MH, Roos KP, Fraser JK, MacLellan WR. Adipose tissue-derived cells improve cardiac function following myocardial infarction. J Surg Res 153(2): 217-223 (2009)
    *Both authors contributed equally to this work.
    Free PMC Article
  29. Evseenko Denis, Schenke-Layland K, Dravid G, Zhu J, Hao QL, Barsky L, Scholes J, Zielinska E, Chao X, Crooks G. Identification of the critical extracellular matrix proteins that promote human embryonic stem cell assembly. Stem Cells Dev 18(6): 919-928 (2009)
  30. Schenke-Layland K. Non-invasive multiphoton imaging of extracellular matrix structures. J Biophotonics 6: 451-462 (2008) (Review)
  31. Brockbank KGM, MacLellan WR, Xie J, Hamm-Alvarez SF, Chen ZZ, Schenke-Layland K. Quantitative Second Harmonic Generation Imaging of Cartilage Damage. Cell Tissue Bank 9: 299-307 (2008)
  32. Heydarkhan-Hagvall S*, Schenke-Layland K*, Dhanasopon A, Rofail F, Smith H, Wu BM, Shemin R, Beygui R, MacLellan WR. Three-dimensional electrospun ECM-based hybrid scaffolds for cardiovascular tissue engineering. Biomaterials 29(19): 2907-2914 (2008)
    *Both authors contributed equally to this work.
    Free PMC Article
  33. Schenke-Layland K, Rhodes KE, Angelis E, Butylkova Y, Gekas C, Mikkola HK, Plath K, MacLellan WR. Reprogrammed mouse fibroblasts differentiate into cells of the cardiovascular and hematopoietic lineages. Stem Cells 26(6): 1537-1546 (2008)
    Free PMC Article
  34. Angelis E, Garcia A, Chan SS Schenke-Layland K, Goodfellow SJ, Xu HJ, Jordan MC, Roos KP, White RJ, MacLellan WR. A Cyclin D2-Rb Pathway Regulates Cardiac Myocyte Size and RNA Polymerase III After Biomechanical Stress in Adult Myocardium. Circ Res 102(10): 1222-1229 (2008)
    Free PMC Article
  35. Heydarkhan-Hagvall S*, Schenke-Layland K*, Yang JQ, Xu Y, Zuk PA, MacLellan WR, Beygui RE. Human adipose stem cells: A potential source for cardiovascular tissue engineering. Cells Tissues Organs 187(4): 263-274 (2008)
    *Both authors contributed equally to this work.
  36. Heydarkhan-Hagvall S, Choi CH, Dunn J, Heydarkhan S, Schenke-Layland K, MacLellan WR, Beygui RE. Influence of systematically varied nano-scale topography on the cell morphology and adhesion. Cell Communication and Adhesion 14(5): 181-194 (2007)
  37. Anderson CD, Heydarkhan-Hagvall S, Schenke-Layland K, Yang JQ, Jordan MC, Kim JK, Brown DA, Zuk PA, Laks H, Roos KP, MacLellan WR, Beygui RE. The Role of Cytoprotective Cytokines in Cardiac Ischemia/Reperfusion Injury. J Surg Res 148(2): 164-171 (2008)
  38. Opitz F, Schenke-Layland K, Cohnert TU, Stock UA. Phenotypical Plasticity of Vascular Smooth Muscle Cells – Impact of in vitro and in vivo Shear Stress for Tissue Engineering of Blood Vessels. Tissue Engineering 13(10): 2505-2514 (2007)
  39. Schenke-Layland K*, Xie J*, Angelis E, Wu K, Riemann I, Starcher B, MacLellan WR, Hamm-Alvarez SF. Increased degradation of extracellular matrix structures of lacrimal glands implicated in the pathogenesis of Sjögren’s syndrome. Matrix Biology 27(1): 53-66 (2008)
    *Both authors contributed equally to this work.
    Free PMC Article
  40. Schenke-Layland K, Xie J,Heydarkhan-Hagvall S, Hamm-Alvarez SF, Stock UA, Brockbank KGM, MacLellan WR. Optimized preservation of extracellular matrix in cardiac tissues: implications for long-term graft durability. Ann Thorac Surg 83(5): 1641-1650 (2007)
  41. Schenke-Layland K, Stock UA. Reply: Can cryopreservation destroy the extracellular matrix of pulmonary allografts? Ann Thorac Surg 83(5): 1921-1922 (2007)
  42. Schenke-Layland K, Angelis E, Rhodes KE, Heydarkhan-Hagvall S, Mikkola HK, MacLellan WR. Collagen IV induces trophoectoderm differentiation of mouse embryonic stem cells. Stem Cells 25(6): 1529-1538 (2007)
    Free Article
  43. Schenke-Layland K, Riemann I, Damour O, Stock UA, König K. Two-photon microscopes and in vivo multiphoton tomographs - Novel diagnostic tools for tissue engineering and drug delivery. Adv Drug Deliv Rev. 58: 878-896 (2006) (Review)
  44. Stock UA, Degenkolbe I, Attmann T, Schenke-Layland K, Freitag S, Lutter G. Prevention of Device Related Tissue Damage during Percutaneous Deployment of Tissue Engineered Heart Valves. J Thorac Cardiovasc Surg 131(6): 1323-1330 (2006)
  45. Schenke-Layland K, Madershahian N, Riemann I, Starcher B, Halbhuber KJ, König K, Stock UA. Impact of cryopreservation on extracellular matrix structures of heart valve leaflets. Ann Thorac Surg 81(3): 918-926 (2006)
  46. Stock UA, Schenke-Layland K. Performance of decellularized xenogeneic tissue in heart valve replacement. Biomaterials 27(1): 1-2 (2006)
  47. Schenke-Layland K, Riemann I, Stock UA, König K. Imaging of cardiovascular structures using NIR femtosecond multiphoton laser scanning microscopy. J Biomed Opt 10(2): 024017 (2005)
  48. Opitz F, Schenke-Layland K, Cohnert TU, Starcher B, Halbhuber KJ, Martin DP, Stock UA. Tissue engineering of aortic tissue: dire consequence of suboptimal elastic fiber synthesis in vivo. Cardiovasc Res 63(4): 719-730 (2004)
    Free Article
  49. Schenke-Layland K, Riemann I, Opitz F, König K, Halbhuber KJ, Stock UA. Comparative Study of Cellular and Extracellular Matrix Composition of Native and Tissue Engineered Heart Valves. Matrix Biology 23(2): 113-125 (2004)
  50. König K*, Schenke-Layland K*, Riemann I, Stock UA. Multiphoton Autofluorescence Imaging of Intratissue Elastic Fibers. Biomaterials 26(5), 495-500 (2005)
    *Both authors contributed equally to this work.
  51. Opitz F, Melle C, Schenke-Layland K, Degenkolbe I, Martin DP, von Eggeling F, Wahlers Th, Stock UA. ProteinChip system technology - A powerful tool to analyze expression differences in tissue engineered blood vessels. Tissue Engineering 10(3/4): 611-620 (2004)
  52. Opitz F, Schenke-Layland K, Richter W, Martin DP, Degenkolbe I, Wahlers T, Stock UA. Tissue engineering of ovine aortic blood vessel substitutes using applied shear stress and enzymatically derived vascular smooth muscle cells. Ann Biomed Eng 32(2): 212-222 (2004)
  53. Schenke-Layland K, Opitz F, Gross M, Doring C, Halbhuber KJ, Schirrmeister F, Wahlers T, Stock UA. Complete dynamic repopulation of decellularized heart valves by application of defined physical signals-an in vitro study. Cardiovasc Res 60(3): 497-509 (2003)
    Free Article
  54. Schenke-Layland K, Vasilevski O, Opitz F, König K, Riemann I, Halbhuber KJ, Wahlers T, Stock UA. Impact of decellularization of xenogeneic tissue on extracellular matrix integrity for tissue engineering of heart valves. J Struct Biol 143(3): 201-208 (2003)
  55. Brenner S, Prösch S, Schenke-Layland K, Riese U, Gausmann U, Platzer C. cAMP-induced Interleukin-10 promoter activation depends on CCAAT/enhancer-binding protein expression and monocytic differentiation. J Biol Chem 278(8): 5597-5604 (2003). Epub 2002 Dec 18
    Free Article